物质信息

ID:181325

MolImageID:132682

Erythromycin estolate

Sigma Aldrich
名称和标识
IUPAC标准名
(3S,4R,5R,6S,7S,9S,12R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione; (dodecyloxy)sulfonic acid
别名
Erythromycin estolateErythromycin 2′-propionate dodecyl sulfate
IUPAC传统名
(3S,4R,5R,6S,7S,9S,12R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione N-dodecyl sulfate
数据登录号
CAS号
3521-62-8
PubChem SID
24894679
化合物性质
安全信息
GHS危险品标识
GHS08
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
GHS07
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
安全公开号
22-36
GHS警示词
Danger
GHS危险声明
H302-H317-H334
德国WGK号
3
危险公开号
22-42/43
GHS警示性声明
P261-P280-P342+P311
欧盟危险性物质标志
有害性 有害性 (Xn)
描述信息
Application
Erythoromycin estolate is used to study hepatic cytochrome P-450 induction and inactivation via cytochrome-metabolite complex formation1 and Giardia intestinalis inefections2. It is used to study antibiotic cytotoxicity in cultured human liver cell lines3.
Biochem/physiol Actions
Erythromycin inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site) by binding to the 50s subunit of the bacterial 70s rRNA complex.
Erythromycin inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site).
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