物质信息
ID:181254
名称和标识
别名
(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-phosphateD-erythro-Sphingosine 1-phosphateSphingosine 1-phosphate
IUPAC标准名
{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}phosphonic acid
IUPAC传统名
sphingosine 1-phosphate
化合物性质
产品相关信息
产品质量级别
PREMIUM
纯度
≥95%
安全信息
欧盟危险性物质标志
刺激性 (Xi)危险公开号
36/37/38
保存温度
-20°C
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
安全公开号
26-36
GHS警示词
Warning
GHS危险声明
H315-H319-H335
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
德国WGK号
3
GHS警示性声明
P261-P305+P351+P338
理化性质
外观
powder
药理学性质
相关基因信息
human ... S1PR1(1901), S1PR2(9294), S1PR3(1903), S1PR4(8698), S1PR5(53637)
描述信息
Biochem/physiol Actions
A lipid second messenger that binds to S1P1 and S1P3 receptors. Mobilizes intracellular Ca2+ stores and decreases cellular cAMP. Activates phospholipase D. S1P stimulates the migration of endothelial cells but inhibits the migration of other cell types. Induces angiogenesis.
A lipid second messenger that binds to S1P1 and S1P3 receptors. Mobilizes intracellular Ca2+ stores and decreases cellular cAMP. Activates phospholipase D. S1P stimulates the migration of endothelial cells but inhibits the migration of other cell types. Induces angiogenesis.
分子图谱
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参考文献
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