物质信息
ID:181233
名称和标识
别名
Tropisetron monohydrochloride3-Tropanylindole-3-carboxylate monohydrochlorideICS-205,930Navobanendo-8-Methyl-8-azabicyclo[3.2.1]oct-3-ol Indol-3-yl-carboxylate 盐酸盐Tropisetron
IUPAC标准名
8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
IUPAC传统名
8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
化合物性质
产品相关信息
纯度
≥98% (HPLC)
安全信息
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
德国WGK号
3
保存温度
2-8°C
药理学性质
相关基因信息
human ... CHRNA3(1136), CHRNA4(1137), CHRNB2(1141), CHRNB4(1143), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242)rat ... Chrna7(25302), Drd2(24318), Htr1a(24473), Htr3a(79246)
理化性质
外观
solid
溶解度
H2O: >10 mg/mL
描述信息
Biochem/physiol Actions
3-Tropanylindole-3-carboxylate hydrochloride is a selective 5-HT3 serotonin receptor antagonist.
Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.
3-Tropanylindole-3-carboxylate hydrochloride is a selective 5-HT3 serotonin receptor antagonist.
Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.
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