物质信息

ID:180694

5-溴-2′-脱氧尿苷

名称和标识
IUPAC传统名
5-bromo-2'-deoxyuridine
别名
5-BrdU5-溴-2′-脱氧尿苷BUdR5-溴-1-(2-脱氧-β-D-呋喃核糖)尿嘧啶5-溴脱氧尿苷5-Bromo-2′-deoxyuridine
IUPAC标准名
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
数据登录号
Beilstein号
CAS号
PubChem SID
化合物性质
产品相关信息
痕量阳离子
NH4+: ≤0.05%
Ca: ≤0.01%
K: ≤0.005%
Na: ≤0.05%
Al: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
Pb: ≤0.001%
Mg: ≤0.0005%
Zn: ≤0.0005%
杂质
≤0.005% Phosphorus (P)
≤0.1% Insoluble matter
燃烧残渣
≤0.1%
纯度
≥99%
安全信息
GHS危险声明
H340-H361
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
德国WGK号
2
GHS警示词
Danger
RTECS编号
YU7350000
GHS危险品标识
GHS08
呼吸道过敏,类别1
生殖细胞突变,类别1A,1B,2
致癌性,类别1A,1B,2
生殖毒性,类别1A,1B,2
特定目标器官毒性 – 一次接触,类别1,2
特定目标器官毒性 – 反复接触,类别1,2
吸入危险,类别1
保存温度
-20°C
GHS警示性声明
P201-P281-P308+P313
理化性质
溶解度
NH4OH: soluble0.1 M at 20 °C, clear, colorless
熔点
191-194 °C (dec.)(lit.)
描述信息
Frequently Asked Questions
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Biochem/physiol Actions
用作遗传研究中诱变剂的胸苷类似物。在 S 期可选择性结合到细胞 DNA 中。
Application
5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
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