Application
Supplementation of cell culture media with glucosamine may enhance N-glycosylation of secreted proteins and affect differentiation of cell lines such as chondocytes and stem cells.
Biochem/physiol Actions
Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids.