物质信息
ID:180234
名称和标识
IUPAC标准名
(3S)-3-{[(1S,2S)-1-{[(1S,2S)-1-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl}-3-[(2S)-2-[(2R)-2-acetamido-3-(1H-indol-3-yl)propanamido]-4-methylpentanamido]propanoic acid
别名
N-Acetyl-[D-Trp16]-Endothelin 1 fragment 16-21
IUPAC传统名
(3S)-3-{[(1S,2S)-1-{[(1S,2S)-1-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl}-3-[(2S)-2-[(2R)-2-acetamido-3-(1H-indol-3-yl)propanamido]-4-methylpentanamido]propanoic acid
化合物性质
药理学性质
相关基因信息
human ... EDN1(1906)rat ... Ednra(24326), Ednrb(50672), Gnrhr(81668)
安全信息
德国WGK号
3
保存温度
-20°C
产品相关信息
主要成分
Dye content, ≥95% HPLC
描述信息
Amino Acid Sequence
Ac-D-Trp-Leu-Asp-Ile-Ile-Trp
Biochem/physiol Actions
ETA antagonist; inhibits ET-1 stimulated arachidonic acid release in rabbit vascular smooth muscle cells.
Ac-D-Trp-Leu-Asp-Ile-Ile-Trp
Biochem/physiol Actions
ETA antagonist; inhibits ET-1 stimulated arachidonic acid release in rabbit vascular smooth muscle cells.
分子图谱
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参考文献
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