物质信息
ID:179401
名称和标识
别名
ThyrocalcitoninCalcitonin rat
IUPAC传统名
3-[(1-{[1-({5-amino-1-[(1-{[1-({1-[(1-{2-[(3-carbamoyl-1-{[1-({1-[(1-{[({1-[({[1-(2-carbamoylpyrrolidin-1-yl)-1-oxopropan-2-yl]carbamoyl}methyl)carbamoyl]-2-methylpropyl}carbamoyl)methyl]carbamoyl}-2-methylbutyl)carbamoyl]-2-hydroxyethyl}carbamoyl)-2-hydroxypropyl]carbamoyl}propyl)carbamoyl]pyrrolidin-1-yl}-1-oxo-3-phenylpropan-2-yl)carbamoyl]-2-hydroxypropyl}carbamoyl)-2-(3H-imidazol-4-yl)ethyl]carbamoyl}-2-phenylethyl)carbamoyl]pentyl}carbamoyl)-2-carbamoylethyl]carbamoyl}-3-methylbutyl)carbamoyl]-3-(2-{2-[2-(2-{2-[2-(2-{[22-amino-16-(carbamoylmethyl)-7-(1-hydroxyethyl)-10-(hydroxymethyl)-13-(2-methylpropyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-4-yl]formamido}-4-(methylsulfanyl)butanamido)-4-methylpentanamido]acetamido}-3-hydroxybutanamido)-3-(4-hydroxyphenyl)propanamido]-3-hydroxybutanamido}-4-carbamoylbutanamido)propanoic acid
IUPAC标准名
3-[(1-{[1-({5-amino-1-[(1-{[1-({1-[(1-{2-[(3-carbamoyl-1-{[1-({1-[(1-{[({1-[({[1-(2-carbamoylpyrrolidin-1-yl)-1-oxopropan-2-yl]carbamoyl}methyl)carbamoyl]-2-methylpropyl}carbamoyl)methyl]carbamoyl}-2-methylbutyl)carbamoyl]-2-hydroxyethyl}carbamoyl)-2-hydroxypropyl]carbamoyl}propyl)carbamoyl]pyrrolidin-1-yl}-1-oxo-3-phenylpropan-2-yl)carbamoyl]-2-hydroxypropyl}carbamoyl)-2-(1H-imidazol-5-yl)ethyl]carbamoyl}-2-phenylethyl)carbamoyl]pentyl}carbamoyl)-2-carbamoylethyl]carbamoyl}-3-methylbutyl)carbamoyl]-3-(2-{2-[2-(2-{2-[2-(2-{[22-amino-16-(carbamoylmethyl)-7-(1-hydroxyethyl)-10-(hydroxymethyl)-13-(2-methylpropyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-4-yl]formamido}-4-(methylsulfanyl)butanamido)-4-methylpentanamido]acetamido}-3-hydroxybutanamido)-3-(4-hydroxyphenyl)propanamido]-3-hydroxybutanamido}-4-carbamoylbutanamido)propanoic acid
化合物性质
安全信息
保存温度
-20°C
德国WGK号
3
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
理化性质
外观
powder
药理学性质
相关基因信息
rat ... Calca(24241)
产品相关信息
纯度
≥95% (HPLC)
描述信息
Amino Acid Sequence
Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Leu-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ser-Ile-Gly-Val-Gly-Ala-Pro-NH2 [Disulfide Bridge: 1-7]
Biochem/physiol Actions
Hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes.
Other Notes
32 amino acid polypeptide, 8 of which are conserved across all species.
Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Leu-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ser-Ile-Gly-Val-Gly-Ala-Pro-NH2 [Disulfide Bridge: 1-7]
Biochem/physiol Actions
Hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes.
Other Notes
32 amino acid polypeptide, 8 of which are conserved across all species.
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