urine (~49% mostly as metabolites, 3% as unchanged drug); feces (~45% mostly as metabolites, 12% as unchanged drug)

via CYP1A2, 2C8, 2C9, UGT1A1, 1A3, 1A9, 2B7

~5-8 hours

Adenuric

~99% to albumin

C

oral

~49% absorbed

Rx-only (US)

Febuxostat