物质信息

ID:138

名称和标识
IUPAC传统名
medrysone
IUPAC标准名
(1S,2R,8S,10S,11S,14S,15S,17S)-14-acetyl-17-hydroxy-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
商标名
HMS LiquifilmMedrifarMedritonicMedrocortHMSVisudrisone
别名
MedrysoneHydroxymesterone
数据登录号
CAS号
PubChem CID
PubChem SID
化合物性质
理化性质
疏水性(logP)
3.2
描述信息
Drug Groups
approved
Description
Medrysone is a corticosteroid used in ophthalmology. [Wikipedia]
Indication
For the treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, and epinephrine sensitivity.
Pharmacology
Medrysone is a topical anti-inflammatory corticoidsteroids for ophthalmic use. In patients with increased intraocular pressure and in those susceptible to a rise in intraocular pressure, there is less effect on pressure with medrysone than with dexamethasone or betamethasone. Corticoidsteroids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as well as capillary proliferation, deposition of collagen, and scar formation.
Affected Organisms
Humans and other mammals
Absorption
Rapidly absorbed following oral administration.
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