物质信息
ID:130810
名称和标识
别名
Z-VD(OMe)VAD(OMe)-FMKZ-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMKZ-Val-Asp(OMe)-Val-Ala-Asp(OMe)-Fluoromethylketone
IUPAC标准名
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methoxy-4-oxobutanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
IUPAC传统名
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methoxy-4-oxobutanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
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描述信息
A cell-permeable and irreversible inhibitor of caspase-2 (ICH-1)
分子图谱
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参考文献
• Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
• Gregoli, P.A., and Bondurant, M.C. 1999. J. Cell Physiol. 178, 133.
• Zhuang, S. et al., Am. J. Physiol. Cell. Physiol., 279(2):C341 (2000).
• Talanian, R.V. et al., J. Biol. Chem., 272(15):9677 (1997).