物质信息
ID:129375
名称和标识
IUPAC标准名
(1S,2R,5S,7R,11S,14S)-11-hydroxy-7-(2-hydroxypropan-2-yl)-1,2-dimethyl-6-oxa-23-azahexacyclo[12.10.0.0?,??.0?,??.0??,??.0??,??]tetracosa-9,16(24),17,19,21-pentaen-8-one
IUPAC传统名
paxilline
别名
PAXILLINE
数据登录号
CAS号
描述信息
From Penicillium paxilli
This fungal mycotoxin possess potent excitatory action on acetylcholine release from nerve terminals. It specifically inhibits smooth muscle high conductance Ca2+ -activated K+ channels, as well as, enhances [125 I]-charybotoxin binding to these channels.
This fungal mycotoxin possess potent excitatory action on acetylcholine release from nerve terminals. It specifically inhibits smooth muscle high conductance Ca2+ -activated K+ channels, as well as, enhances [125 I]-charybotoxin binding to these channels.
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参考文献
• Knaus, et al., Biochemistry , 33 : 5819 (1994).