物质信息
ID:1249
名称和标识
别名
AntipyrinePhenazonPyrazolineAnalgesineAnodynineAzophenAntipyrinAzophenumFenazon [czech]PhenozoneAcetasolFenazonePhenazoneAnodyninAntipirinAntipyrinumFenazona [inn-spanish]
IUPAC标准名
1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
IUPAC传统名
antipyrine
商标名
AuralganSedatineApirelinaSedatin
化合物性质
理化性质
溶解度
51.9 mg/mL at 25 oC [YALKOWSKY,SH & DANNENFELSER,RM (1992)]
疏水性(logP)
0.38 [HANSCH,C ET AL. (1995)]
描述信息
Drug Groups
approved
Description
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Indication
Antipyrine is an analgesic often used to test effects of other drugs on liver enzymes..
Pharmacology
Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Affected Organisms
Humans and other mammals
External Links
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