物质信息
ID:1245
名称和标识
别名
Almitrine dimesylateAlmitrine bismesylateAlmitrineAlmitrine mesylate
商标名
VectarionDuxilDoxil
IUPAC传统名
almitrine
IUPAC标准名
6-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-2-N,4-N-bis(prop-2-en-1-yl)-1,3,5-triazine-2,4-diamine
化合物性质
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描述信息
Drug Groups
approved
Description
A respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep. [PubChem]
Indication
For the treatment of chronic obstructive pulmonary disease.
Pharmacology
Almitrine is a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.
Affected Organisms
Humans and other mammals
External Links
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参考文献
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