物质信息
ID:1153
名称和标识
IUPAC传统名
bevantololum
IUPAC标准名
[2-(3,4-dimethoxyphenyl)ethyl][2-hydroxy-3-(3-methylphenoxy)propyl]amine
别名
Bevantololum [inn-latin]1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanolBevantolol
化合物性质
理化性质
疏水性(logP)
3.00 [HANSCH,C ET AL. (1995)]
描述信息
Drug Groups
approved
Description
Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.
Indication
For the treatment of angina pectoris and hypertension.
Pharmacology
Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension.
Affected Organisms
Humans and other mammals
References
•
Vaughan Williams EM: Bevantolol: a beta-1 adrenoceptor antagonist with unique additional actions. J Clin Pharmacol. 1987 Jul;27(7):450-60.
[Pubmed]
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参考文献
• Vaughan Williams EM: Bevantolol: a beta-1 adrenoceptor antagonist with unique additional actions. J Clin Pharmacol. 1987 Jul;27(7):450-60. Pubmed