物质信息

ID:1134

名称和标识
商标名
DesocortDesowenTridesilonDesilux
别名
Desonide
IUPAC标准名
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-16-one
IUPAC传统名
desonide
数据登录号
CAS号
PubChem CID
PubChem SID
化合物性质
理化性质
疏水性(logP)
1.4
溶解度
Practically insoluble
描述信息
Drug Groups
approved; investigational
Description
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. [PubChem]
Indication
For the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatose.
Pharmacology
Desonide is a synthetic nonfluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.
Affected Organisms
Humans and other mammals
Absorption
Topical corticosteroids can be absorbed from normal intact skin, inflammation and/or other disease processes in the skin may increase percutaneous absorption.
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