物质信息
ID:106
名称和标识
商标名
Beta-2BronkometerBronkosolDey-Lute IsoetharineIsoetharine HCl S/FNeoisuprelEtyprenalineIsoetarinDilabronIsoetarine
别名
Isoetarina [INN-Spanish]Isoetarinum [INN-Latin]Isoetharine HclIsoetharine mesylateIsoetharine
IUPAC标准名
4-{1-hydroxy-2-[(propan-2-yl)amino]butyl}benzene-1,2-diol
IUPAC传统名
isoetarine
化合物性质
理化性质
疏水性(logP)
2.2
溶解度
Appreciable
描述信息
Drug Groups
approved
Description
Isoetharine is a selective adrenergic beta-2 agonist used as fast acting bronchodilator for emphysema, bronchitis and asthma. [PubChem]
Indication
For the treatment of asthma, wheezing, and chronic asthmatic bronchitis.
Pharmacology
Isoetharine is a relatively selective beta2-adrenergic bronchodilator. Isoetharine is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease. Adrenergic bronchodilators are breathed in through the mouth to open up the bronchial tubes (air passages) of the lungs.
Toxicity
Signs of overdose include tachycardia, palpitations, nausea, headache, and epinephrine-like side effects.
Affected Organisms
Humans and other mammals
References
•
Emerman CL, Cydulka RK, Effron D, Lukens TW, Gershman H, Boehm SP: A randomized, controlled comparison of isoetharine and albuterol in the treatment of acute asthma. Ann Emerg Med. 1991 Oct;20(10):1090-3.
[Pubmed]
External Links
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参考文献
• Emerman CL, Cydulka RK, Effron D, Lukens TW, Gershman H, Boehm SP: A randomized, controlled comparison of isoetharine and albuterol in the treatment of acute asthma. Ann Emerg Med. 1991 Oct;20(10):1090-3. Pubmed