Substance

ID:964

Names and Identifiers
IUPAC name
methyl (1R,15S,17R,18R,19S,20S)-18-methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
Synonyms
DeserpineDeserpidineDeserpidina [INN-Spanish]Deserpidinum [INN-Latin]DeresperineDesmethoxyreserpineDeserpidinDesepridine
Brand Name
AescinCanescineRecanescinRecanescineCanescinEnduronylHarmonylRaunorminRaunorminebeta-EscinRaunorineReserpidineTranquinil
IUPAC Traditional name
methyl (1R,15S,17R,18R,19S,20S)-18-methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
Registration numbers
PubChem SID
PubChem CID
CAS Number
Properties
Physical Property
Hydrophobicity(logP)
3.3
Molecule Details
Drug Groups
approved
Description
Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.
Indication
For the treatment of hypertension.
Pharmacology
Deserpidine, an alkaloid of Rauwolfia canescens, is used as an antihypertensive. Rauwolfia alkaloids work by controlling nerve impulses along certain nerve pathways. As a result, they act on the heart and blood vessels to lower blood pressure.
Toxicity
Symptoms of overdose include dizziness or drowsiness (severe), flushing of skin, pinpoint pupils of eyes and slowed pulse.
Affected Organisms
Humans and other mammals
Molecular Spectra
No Data Available
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References
No Data Available
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