Deslanoside

Names and Identifiers

Brand Name

Deacetyllanatoside CCedilanid-d

IUPAC name

4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-11,16-dihydroxy-5-{[(2R,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]-2,5-dihydrofuran-2-one

Synonyms

Deslanoside

IUPAC Traditional name

deslanoside

Registration numbers

CAS Number

17598-65-1

Properties

Physical Property

Hydrophobicity(logP)

0.2

Molecule Details

Drug Groups

approved

Description

Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata. [PubChem]

Indication

For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.

Pharmacology

Deslanoside is a cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation.

Toxicity

Symptoms of overdose include ventricular tachycardia, ventricular fibrillation, progressive bradyarrhythmias, or heart block.

Affected Organisms

Humans and other mammals

Absorption

Little absorption from the gastrointestinal tract (40%).

Half Life

36 hours

Protein Binding

20%

External Links

• [Wikipedia]