Substance

ID:930

Names and Identifiers
IUPAC name
(2S)-2-amino-3-(3-hydroxy-4-oxo-1,4-dihydropyridin-1-yl)propanoic acid
IUPAC Traditional name
mimosine
Synonyms
LeucenineL-MimosineLeucaenineMimosinMimosineLeucaenolLeucenol
Registration numbers
CAS Number
PubChem CID
PubChem SID
Properties
Physical Property
Hydrophobicity(logP)
-2.5
Molecule Details
Drug Groups
approved
Description
3-Hydroxy-4-oxo-1(4H)-pyridinealanine. An antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca. [PubChem]
Pharmacology
Mimosine inhibits DNA synthesis at the level of elongation of nascent chains by altering deoxyribonucleotide metabolism. It arrests the cell cycle in the late G(1) phase.
Affected Organisms
Humans and other mammals
Protein Binding
>99.5%
External Links
Molecular Spectra
No Data Available
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References
No Data Available
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