Oxybuprocaine

Names and Identifiers

Brand Name

BenoxilDorsacainFluressNovesinaNovesinolCebesinePrescainaConjucainLacriminOpulets BenoxinateMinims BenoxinateNovesinNovesineConjuncainDorsacaine

IUPAC name

2-(diethylamino)ethyl 4-amino-3-butoxybenzoate

Synonyms

Oxybuprocaine HCLOxybuprocaine hydrochlorideOxybucaineOxibuprocainumOxbarukainDorsacaine hydrochlorideBenoxinate hydrochlorideBenoxinate HCLOxybuprocaineOxyriprocaineOxibuprokainBenoxinate

IUPAC Traditional name

oxybuprocaine

Registration numbers

PubChem CID

4633

PubChem SID

46505399

CAS Number

99-43-4

Properties

Physical Property

Hydrophobicity(logP)

3.1

Solubility

Very soluble (hydrochloride salt)

Molecule Details

Drug Groups

approved

Description

Oxybuprocaine is the name of a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.

Indication

Used to temporarily numb the front surface of the eye so that the eye pressure can be measured or a foreign body removed.

Pharmacology

Oxybuprocaine is a local anaesthetic. It may be less irritating than tetracaine, and the onset and duration of action are similar to tetracaine.

Affected Organisms

Humans and other mammals

External Links

• [Wikipedia]

• [RxList]

Molecular Spectra

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