Substance
ID:74198
Names and Identifiers
Synonyms
10-Deacetylbaccatin10-DAB
IUPAC Traditional name
10-deacetylbaccatin
IUPAC name
(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-1,9,12,15-tetrahydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10}.0^{4,7}]heptadec-13-en-2-yl benzoate
Registration numbers
CAS Number
Properties
Product Information
Salt Data
Free Base
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: cancer
Biological Activity:
10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate. 10-DAB (10-Deacetylbaccatin) has gained great attention because of its partly excellent anti-cancer properties. 10-DAB (10-Deacetylbaccatin) can be gained from the leaves of yew trees and 10-DAB (10-Deacetylbaccatin) is used as starting materials for numerous partial syntheses. The esterification of 10-DAB (10-Deacetylbaccatin) with longchain fatty acids can also generate an important enhancement of their kinetics and consequently their pharmacological action pattern. 10-DAB (10-Deacetylbaccatin) was first succinylated by use of dimethylaminopyridine and succinic anhydride in dried pyridine. [1][2]References on 10-DAB (10-Deacetylbaccatin)[1] Nat Prod Res. , 2006 Feb, 20(2):119-24[2] Biol Pharm Bull. , 2011, 34(4):562-6
Biological Activity:
10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate. 10-DAB (10-Deacetylbaccatin) has gained great attention because of its partly excellent anti-cancer properties. 10-DAB (10-Deacetylbaccatin) can be gained from the leaves of yew trees and 10-DAB (10-Deacetylbaccatin) is used as starting materials for numerous partial syntheses. The esterification of 10-DAB (10-Deacetylbaccatin) with longchain fatty acids can also generate an important enhancement of their kinetics and consequently their pharmacological action pattern. 10-DAB (10-Deacetylbaccatin) was first succinylated by use of dimethylaminopyridine and succinic anhydride in dried pyridine. [1][2]References on 10-DAB (10-Deacetylbaccatin)[1] Nat Prod Res. , 2006 Feb, 20(2):119-24[2] Biol Pharm Bull. , 2011, 34(4):562-6
Molecular Spectra
No Data Available
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References
• Muto S et al. Biol Pharm Bull. 2011; 34(4):562-6.