Substance
ID:74187
Names and Identifiers
Synonyms
LevophedNoradrenaline bitartrate monohydrate
IUPAC Traditional name
L-tartaric acid norepinephrine hydrate
IUPAC name
(2R,3R)-2,3-dihydroxybutanedioic acid 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol hydrate
Registration numbers
CAS Number
Properties
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Endocrinology
Biological Activity:
Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.Noradrenaline bitartrate monohydrate (Levophed) also directly stimulates the beta-adrenergic receptors of the heart (beta1-adrenergic receptors), but not those of the bronchi (beta2-adrenergic receptors). Noradrenaline functions as a peripheral vasoconstrictor (alpha-adrenergic action) and as an inotropic stimulator of the heart and dilator of coronary arteries (beta-adrenergic action). These actions result in an increase in the force of myocardial contraction, increase in peripheral resistance and a rise in diastolic and systolic pressures. [1][2]References on Noradrenaline bitartrate monohydrate (Levophed)[1] http://en.wikipedia.org/wiki/Norepinephrine, , [2] Proc Natl Acad Sci U S A., 2010 Mar 30, 107(13):6058-63
Biological Activity:
Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.Noradrenaline bitartrate monohydrate (Levophed) also directly stimulates the beta-adrenergic receptors of the heart (beta1-adrenergic receptors), but not those of the bronchi (beta2-adrenergic receptors). Noradrenaline functions as a peripheral vasoconstrictor (alpha-adrenergic action) and as an inotropic stimulator of the heart and dilator of coronary arteries (beta-adrenergic action). These actions result in an increase in the force of myocardial contraction, increase in peripheral resistance and a rise in diastolic and systolic pressures. [1][2]References on Noradrenaline bitartrate monohydrate (Levophed)[1] http://en.wikipedia.org/wiki/Norepinephrine, , [2] Proc Natl Acad Sci U S A., 2010 Mar 30, 107(13):6058-63
Molecular Spectra
No Data Available
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References
• Heneka MT et al. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63.