Substance
ID:73953
Names and Identifiers
Synonyms
Ascorbyl monopalmitateL-Ascorbyl 6-palmitateAscorbic palmitate
IUPAC Traditional name
ascorbyl palmitate
IUPAC name
(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl]-2-hydroxyethyl hexadecanoate
Registration numbers
CAS Number
Properties
Safety Information
Storage Condition
-20°C
Product Information
Salt Data
Free Base
Molecule Details
Research Area: Cancer
Biological Activity:
L-Ascorbyl 6-palmitate is a synthetic lipophilic ascorbic acid derivative. L-Ascorbyl 6-palmitate is an effective preservative in foods and an effective dietary antitumor promoter in mice. Studies indicate that dietary AP is a source of tissue vitamin C in animals. Besides, dietary L-Ascorbyl 6-palmitate possesses weak antiscorbutic activity in guinea pigs and enhances vitamin C nutriture in humans. In a study, daily mean weight loss during repletion in control animals receiving placebo was significantly greater than that for both L-ascorbic acid (AA) and L-Ascorbyl 6-palmitate animals for days 3–10 of repletion. Daily mean weight loss for AP animals was significantly greater than that for AA animals on days 5 and 6 of repletion. By comparing areas of the weight-time curve during repletion, L-Ascorbyl 6-palmitate appeared to be about 50% as effective as AA in reversing scurvy. [1]
Biological Activity:
L-Ascorbyl 6-palmitate is a synthetic lipophilic ascorbic acid derivative. L-Ascorbyl 6-palmitate is an effective preservative in foods and an effective dietary antitumor promoter in mice. Studies indicate that dietary AP is a source of tissue vitamin C in animals. Besides, dietary L-Ascorbyl 6-palmitate possesses weak antiscorbutic activity in guinea pigs and enhances vitamin C nutriture in humans. In a study, daily mean weight loss during repletion in control animals receiving placebo was significantly greater than that for both L-ascorbic acid (AA) and L-Ascorbyl 6-palmitate animals for days 3–10 of repletion. Daily mean weight loss for AP animals was significantly greater than that for AA animals on days 5 and 6 of repletion. By comparing areas of the weight-time curve during repletion, L-Ascorbyl 6-palmitate appeared to be about 50% as effective as AA in reversing scurvy. [1]
Molecular Spectra
No Data Available
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References
• Jonker D et al. Toxicology. 1988 Nov 30; 52(3)