Substance
ID:73925
Names and Identifiers
Synonyms
Oxymetazoline
IUPAC name
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol hydrochloride
IUPAC Traditional name
oxymetazoline hydrochloride
Registration numbers
CAS Number
Properties
Safety Information
Storage Condition
-20°C
Product Information
Salt Data
hydrochloride
Molecule Details
Research Area: Cardiovascular Disease
Biological Activity:
Oxymetazoline hydrochloride is an α1 and α2 adrenergic receptor agonist. It is available over-the-counter as a topical decongestant in nasal sprays. The action of oxymetazoline results in vasoconstriction. In addition, the local application of the drug also results in vasoconstriction due to its action on endothelial postsynaptic α2 receptors; systemic application of α2 agonists, in contrast, causes vasodilation because of centrally-mediated inhibition of sympathetic tone via presynaptic α2 receptors. [1]
Biological Activity:
Oxymetazoline hydrochloride is an α1 and α2 adrenergic receptor agonist. It is available over-the-counter as a topical decongestant in nasal sprays. The action of oxymetazoline results in vasoconstriction. In addition, the local application of the drug also results in vasoconstriction due to its action on endothelial postsynaptic α2 receptors; systemic application of α2 agonists, in contrast, causes vasodilation because of centrally-mediated inhibition of sympathetic tone via presynaptic α2 receptors. [1]
Molecular Spectra
No Data Available
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References
• http://en.wikipedia.org/wiki/Oxymetazoline