Substance
ID:73906
Names and Identifiers
IUPAC name
(2-{2,3-bis[2-(triethylazaniumyl)ethoxy]phenoxy}ethyl)triethylazanium triiodide
Synonyms
Gallamine triethiodide Flaxedil
IUPAC Traditional name
(2-{2,3-bis[2-(triethylaminio)ethoxy]phenoxy}ethyl)triethylazanium triiodide
Registration numbers
CAS Number
Properties
Safety Information
Storage Condition
-20°C
Product Information
Salt Data
Iodine salt
Molecule Details
Research Area: Neurological Disease
Biological Activity:
Gallamine triethiodide(Flaxedil) is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 µM. It is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. It has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. [1][2]
Biological Activity:
Gallamine triethiodide(Flaxedil) is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 µM. It is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. It has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. [1][2]
Molecular Spectra
No Data Available
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References
• Dunn PM et al. Br J Pharmacol. 1996 Jan;117(1)