Substance
ID:73854
Names and Identifiers
IUPAC Traditional name
yohimbine hydrochloride
Synonyms
AntagonilYohimbeYohimbine monohydrochlorideYohimbine hydrochlorideAphrodine hydrochloride
IUPAC name
methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate hydrochloride
Registration numbers
CAS Number
Properties
Product Information
Salt Data
ydrochloride
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Endocrinology
Biological Activity:
Yohimbine(Antagonil) has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac. Yohimbine is a pre-synaptic alpha 2-adrenergic blocking agent. Yohimbine may exert its beneficial effect on erectile ability through blockade of central alpha 2-adrenergic receptors producing an increase in sympathetic drive secondary to an increase in norepinephrine release and in firing rate of cells in the brain noradrenergic nuclei. [1]
Biological Activity:
Yohimbine(Antagonil) has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac. Yohimbine is a pre-synaptic alpha 2-adrenergic blocking agent. Yohimbine may exert its beneficial effect on erectile ability through blockade of central alpha 2-adrenergic receptors producing an increase in sympathetic drive secondary to an increase in norepinephrine release and in firing rate of cells in the brain noradrenergic nuclei. [1]
Molecular Spectra
No Data Available
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References
• http://www.drugbank.ca/drugs/DB01392