Substance
ID:737226
Names and Identifiers
IUPAC name
N-(benzenesulfonyl)-S-phenylfluoranesulfonamido
IUPAC Traditional name
N-(benzenesulfonyl)-S-phenylfluoranesulfonamido
Synonyms
N-氟苯磺酰亚胺N-FluorobenzenesulfonimideN-Fluorobis(phenylsulfonyl)amineAccuFluor NFSi
Registration numbers
CAS Number
MDL Number
Beilstein Number
EC Number
Properties
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
TSCA Listed
否
Risk Statements
36/37/38
GHS Hazard statements
H315-H319-H335
European Hazard Symbols
Irritant (Xi)Safety Statements
26-37
GHS Precautionary statements
P261-P305+P351+P338-P302+P352-P321-P405-P501A
Product Information
Purity
97%
Physical Property
Melting Point
114-118°C
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• For directed fluorination of ortho-lithiated aromatics, see: Tetrahedron Lett., 35, 3465 (1994); ɑɑ-difluorination of benzylic phosphonate anions: Tetrahedron, 54, 1691 (1998); andof benzylic nitriles, tetrazoles and sulfonates: J. Org. Chem., 63, 8052 (1998).
• For a review of electrophilic N-F fluorinating agents, see: Chem. Rev., 96, 1737 (1996).
• Stable, non-hygroscopic, glass-compatible mild electrophilic fluorinating agent, very soluble in acetonitrile, dichloromethane or THF, less soluble in toluene. Fluorinates aromatics, enolates, azaenolates and carbanions in high yield: Synlett, 187, 395 (1991); Tetrahedron Lett., 32, 1631 (1991); for diastereoselective fluorination of Li enolates of chiral carboximides, see: Tetrahedron Lett., 33, 1153 (1992). Asymmteric fluorinations have been effected in the presence of a Pd-BINAP catalyst system at room temperature in an ionic liquid: Org. Lett., 5, 3225 (2003).