Substance
ID:737164
Names and Identifiers
IUPAC name
(2S)-2-amino-3,3-dimethylbutanoic acid
IUPAC Traditional name
(2S)-2-amino-3,3-dimethylbutanoic acid
Synonyms
L-tert-LeucineL-叔亮氨酸(S)-2-Amino-3,3-dimethylbutyric acidL-2-tert-Butylglycine
Registration numbers
MDL Number
CAS Number
Beilstein Number
EC Number
Properties
Product Information
Purity
99%
Physical Property
Optical Rotation
+7 (c=5 in 5N HCl)
Melting Point
>300°C
Safety Information
TSCA Listed
否
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• ɑ-Amino acids have been used in combination with NaBH4 for the asymmetric reduction of ketones. Of a number of amino acids the sterically hindered tert-leucine was found to give the highest ee (95%) in the reduction of the carbonyl group of a 1,5-benzothiazepine intermediate in an efficient synthesis of the calcium antagonist diltiazem: J. Org. Chem., 61, 8586 (1996).