Substance
ID:73657
Names and Identifiers
IUPAC Traditional name
butanoic acid, sodium salt
IUPAC name
sodium butanoate
Synonyms
Butyric acid sodium saltSodium butyrate
Registration numbers
CAS Number
Properties
Physical Property
Solubility
DMSO
Safety Information
Storage Condition
-20°C
Product Information
Salt Data
Butyrate
Molecule Details
Research Area: Cancer
Biological Activity:
Sodium butyrate is a compound with formula Na(C3H7COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. As such, it can be used in lab to bring about any of these effects. Specifically, butyrate treatment of cells results in histone hyperacetylation, and butyrate itself inhibits HDAC activity. Butyrate has been an essential vehicle for determining the role of histone acetylation in chromatin structure and function. Inhibition of HDAC activity affects the expression of only 2% of mammalian genes. [1]
Biological Activity:
Sodium butyrate is a compound with formula Na(C3H7COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. As such, it can be used in lab to bring about any of these effects. Specifically, butyrate treatment of cells results in histone hyperacetylation, and butyrate itself inhibits HDAC activity. Butyrate has been an essential vehicle for determining the role of histone acetylation in chromatin structure and function. Inhibition of HDAC activity affects the expression of only 2% of mammalian genes. [1]
Molecular Spectra
No Data Available
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References
• http://en.wikipedia.org/wiki/Sodium_butyrate