Substance
ID:73644
Names and Identifiers
Synonyms
Vitamin K3Menadione
IUPAC name
2-methyl-1,4-dihydronaphthalene-1,4-dione
IUPAC Traditional name
menadione
Registration numbers
CAS Number
Properties
Product Information
Salt Data
Free Base
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Endocrinology
Biological Activity:
Menadione(Vitamin K3), a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone,after alkylation in vivo. Menadione (vitamin K3) is involved as a cofactor in the posttranslational gamma-carboxylation of glutamic acid residues of certain proteins in the body. These proteins include the vitamin K-dependent coagulation factors II (prothrombin), VII (proconvertin), IX (Christmas factor), X (Stuart factor), protein C, protein S, protein Zv and a growth-arrest-specific factor (Gas6). [1]
Biological Activity:
Menadione(Vitamin K3), a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone,after alkylation in vivo. Menadione (vitamin K3) is involved as a cofactor in the posttranslational gamma-carboxylation of glutamic acid residues of certain proteins in the body. These proteins include the vitamin K-dependent coagulation factors II (prothrombin), VII (proconvertin), IX (Christmas factor), X (Stuart factor), protein C, protein S, protein Zv and a growth-arrest-specific factor (Gas6). [1]
Molecular Spectra
No Data Available
Click here to submit data
References
• http://www.drugbank.ca/drugs/DB00170