Substance
ID:736101
Names and Identifiers
IUPAC Traditional name
DMPU
Synonyms
N,N'-Dimethylpropyleneurea1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinoneDMPU1,3-二甲基-3,4,5,6-四氢-2(1H)-嘧啶酮
IUPAC name
1,3-dimethyl-1,3-diazinan-2-one
Registration numbers
EC Number
MDL Number
CAS Number
Beilstein Number
Properties
Safety Information
RTECS
UW7582500
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Safety Statements
26-36/37/39
TSCA Listed
是
European Hazard Symbols
Harmful (X)GHS Precautionary statements
P280-P301+P310-P305+P351+P338-P321-P405-P501A
Storage Warning
Hygroscopic
Risk Statements
22-41-62
GHS Hazard statements
H301-H318-H361
Product Information
Purity
98%
Physical Property
Density
1.060
Melting Point
-23°C
Flash Point
120°C(248°F)
Boiling Point
246-247°C
Refractive Index
1.4890
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Has been found to be comparable to HMPA in promoting reductive coupling reactions with SmI2: J. Am. Chem. Soc., 110, 5064 (1988); J. Chem. Soc., Chem. Commun., 1775 (1992), and also in other reductions with the same reagent: J. Org. Chem., 58, 5008 (1993).
• Dipolar aprotic solvent recommended as a replacement for the carcinogenic hexamethylphosphoric triamide (HMPA) in many reactions: Helv. Chim. Acta, 65, 385 (1982). DMPU is non-mutagenic: Chimia, 39, 148 (1985). It is more useful than the lower homologue 1,3-Dimethyl-2-imidazolidinone, A16001 (mp 8oC) for low-temperature reactions. Can be used as a general replacement for HMPA in organolithium reactions: J. Am. Chem. Soc., 107, 719 (1985).