Substance
ID:73558
Names and Identifiers
IUPAC Traditional name
thiabendazole
IUPAC name
2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole
Synonyms
EquizoleThiabendazoleMintezol
Registration numbers
CAS Number
Properties
Safety Information
Storage Condition
-20°C
Product Information
Salt Data
Free Base
Molecule Details
Research Area: Infection
Biological Activity:
Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with possible interaction with endogenous quinone. [1]A benzimidazole derivative with anthelminthic property. Thiabendazole inhibits the helminth-specific mitochondrial enzyme fumarate reductase, thereby inhibiting the citric acid cycle, mitochondrial respiration and subsequent production of ATP, ultimately leading to helminth’s death. [2]
Biological Activity:
Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with possible interaction with endogenous quinone. [1]A benzimidazole derivative with anthelminthic property. Thiabendazole inhibits the helminth-specific mitochondrial enzyme fumarate reductase, thereby inhibiting the citric acid cycle, mitochondrial respiration and subsequent production of ATP, ultimately leading to helminth’s death. [2]
Molecular Spectra
No Data Available
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References
• http://en.wikipedia.org/wiki/Tiabendazole