Substance
ID:73549
Names and Identifiers
IUPAC name
5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid
IUPAC Traditional name
gemfibrozil
Synonyms
GemfibrozilLopidJezilGemcorGen-Fibro
Registration numbers
CAS Number
Properties
Product Information
Salt Data
Free Base
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Cardiovascular Disease
Biological Activity:
Gemfibrozil (Lopid) is an oral drug used to lower lipid levels. It belongs to a group of drugs known as fibrates. Increases activity of Peroxisome proliferator-activated receptor-alpha (PPARα) ’transcription factor ligand’ , a receptor that is involved in metabolism of carbohydrates and fats, as well as adipose tissue differentiation. This increase in the synthesis of lipoprotein lipase thereby increases the clearance of triglycerides. [1]
Biological Activity:
Gemfibrozil (Lopid) is an oral drug used to lower lipid levels. It belongs to a group of drugs known as fibrates. Increases activity of Peroxisome proliferator-activated receptor-alpha (PPARα) ’transcription factor ligand’ , a receptor that is involved in metabolism of carbohydrates and fats, as well as adipose tissue differentiation. This increase in the synthesis of lipoprotein lipase thereby increases the clearance of triglycerides. [1]
Molecular Spectra
No Data Available
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References
• www.bentham.org/prc/samples/prc1-1/Higashi.pdf