Substance
ID:73520
Names and Identifiers
Synonyms
BiltricidePraziquantelDroncit
IUPAC Traditional name
praziquantel
IUPAC name
2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-piperazino[2,1-a]isoquinolin-4-one
Registration numbers
CAS Number
Properties
Product Information
Salt Data
Free Base
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Infection
Biological Activity:
Praziquantel(Biltricide, Droncit) is an anthelmintic effective against flatworms. It increases the permeability of the membranes of schistosome cells towards calcium ions. The drug， thereby induces contraction of the parasites, resulting in paralysis in the contracted state. The dying parasites are dislodged from their site of action in the host organism and may enter systemic circulation or may be destroyed by host immune reaction (phagocytosis). Additional mechanisms including focal disintegrations and disturbances of oviposition (laying of eggs) are seen in other types of sensitive parasites. [1]
Biological Activity:
Praziquantel(Biltricide, Droncit) is an anthelmintic effective against flatworms. It increases the permeability of the membranes of schistosome cells towards calcium ions. The drug， thereby induces contraction of the parasites, resulting in paralysis in the contracted state. The dying parasites are dislodged from their site of action in the host organism and may enter systemic circulation or may be destroyed by host immune reaction (phagocytosis). Additional mechanisms including focal disintegrations and disturbances of oviposition (laying of eggs) are seen in other types of sensitive parasites. [1]
Molecular Spectra
No Data Available
Click here to submit data
References
• http://en.wikipedia.org/wiki/Praziquantel