Substance

ID:734913

Names and Identifiers
IUPAC name
5-amino-1,2,3,4-tetrahydropyrimidine-2,4-dione
IUPAC Traditional name
5-amino-1,3-dihydropyrimidine-2,4-dione
Synonyms
5-Amino-2,4-dihydroxypyrimidine5-Aminouracil5-氨基脲嘧啶
Registration numbers
CAS Number
MDL Number
Beilstein Number
EC Number
Properties
Safety Information
GHS Pictograms
GHS06
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Safety Statements
36
GHS Precautionary statements
P264-P270-P301+P310-P321-P405-P501A
TSCA Listed
European Hazard Symbols
Harmful Harmful (X)
Risk Statements
22
RTECS
YQ8740000
GHS Hazard statements
H301
Physical Property
Melting Point
>300°C
Product Information
Purity
97%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Condensation with crotonaldehyde gives 2,4-dioxo-6-methylpyrido[3,2-d]pyrimidine: J. Chem. Soc. (C), 1745 (1967). An improved procedure has been used in synthesis of inhibitors of human thymidylate synthase: J. Med. Chem., 27, 1710 (1984), and of dihydrofolate reductases: J. Med. Chem., 39, 1836 (1996):
• Review of the use of uracils as starting materials in heterocyclic synthesis: Adv. Heterocycl. Chem., 55, 130 (1992).