Substance
ID:73455
Names and Identifiers
IUPAC Traditional name
lotrimin
IUPAC name
1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole
Synonyms
CanestenClotrimazole(Canesten)LotriminMycelex
Registration numbers
CAS Number
Properties
Safety Information
Storage Condition
-20°C
Product Information
Salt Data
Free Base
Physical Property
Solubility
DMSO
Molecule Details
Research Area: Infection
Biological Activity:
Clotrimazole(Canesten) is a synthetic, antifungal and broad-spectrum derivate of imidazole. Clotrimazole inhibits biosynthesis of sterols, particularly inhibiting ergosterol, which is an essential component of the fungal cell membrane, thereby damaging and affecting the permeability of the cell membrane. This results in the leakage and the loss of essential intracellular compounds, and eventually causes the lysis of cell. [1, 2]
Biological Activity:
Clotrimazole(Canesten) is a synthetic, antifungal and broad-spectrum derivate of imidazole. Clotrimazole inhibits biosynthesis of sterols, particularly inhibiting ergosterol, which is an essential component of the fungal cell membrane, thereby damaging and affecting the permeability of the cell membrane. This results in the leakage and the loss of essential intracellular compounds, and eventually causes the lysis of cell. [1, 2]
Molecular Spectra
No Data Available
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References
• http://en.wikipedia.org/wiki/Clotrimazole