Substance
ID:73445
Names and Identifiers
Synonyms
WIN 48098Pravadoline(WIN 48098)
IUPAC Traditional name
3-(4-methoxybenzoyl)-2-methyl-1-[2-(morpholin-4-yl)ethyl]indole
IUPAC name
3-(4-methoxybenzoyl)-2-methyl-1-[2-(morpholin-4-yl)ethyl]-1H-indole
Registration numbers
CAS Number
Properties
Product Information
Salt Data
Free Base
Pharmacology Properties
Target
COX
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Neurological Disease
Biological Activity:
Pravadoline (WIN 48098) is an antiinflammatory and analgesic compound with an IC50 of 4.9 µM for inhibition of the synthesis of prostaglandins (PGs) in mouse brain. Pravadoline (WIN 48098) is related in structure to non-steroidal antinflammtory agents such as indometacin. Pravadoline (WIN 48098) was developed in the 1980s as a new antiinflammatory and prostaglandin synthesis inhibitor, acting through inhibition of the enzyme cyclooxygenase (COX). [1][2]References on Pravadoline (WIN 48098)[1] J Pharmacol Exp Ther., 1990 Nov, 255(2):511-22.[2] http://en.wikipedia.org/wiki/Pravadoline, ,
Biological Activity:
Pravadoline (WIN 48098) is an antiinflammatory and analgesic compound with an IC50 of 4.9 µM for inhibition of the synthesis of prostaglandins (PGs) in mouse brain. Pravadoline (WIN 48098) is related in structure to non-steroidal antinflammtory agents such as indometacin. Pravadoline (WIN 48098) was developed in the 1980s as a new antiinflammatory and prostaglandin synthesis inhibitor, acting through inhibition of the enzyme cyclooxygenase (COX). [1][2]References on Pravadoline (WIN 48098)[1] J Pharmacol Exp Ther., 1990 Nov, 255(2):511-22.[2] http://en.wikipedia.org/wiki/Pravadoline, ,
Molecular Spectra
No Data Available
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References
• http://en.wikipedia.org/wiki/Pravadoline