Substance
ID:734178
Names and Identifiers
IUPAC Traditional name
1,3-diethyl 2-bromo-2-methylpropanedioate
IUPAC name
1,3-diethyl 2-bromo-2-methylpropanedioate
Synonyms
Diethyl 2-bromo-2-methylmalonate2-Bromo-2-methylmalonic acid diethyl ester2-溴代-2-甲基丙二酸二乙酯
Registration numbers
EC Number
CAS Number
MDL Number
Beilstein Number
Properties
Physical Property
Density
1.323
Refractive Index
1.4490
Boiling Point
105-106°C/5mm
Flash Point
>110°C(230°F)
Safety Information
TSCA Listed
否
GHS Precautionary statements
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
Packing Group
II
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Safety Statements
26-36/37/39-45
Hazard Class
8
UN Number
UN3265
European Hazard Symbols
Corrosive (C)Risk Statements
34
GHS Hazard statements
H314-H318
Product Information
Purity
98%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Reacts with nucleophiles at bromine with displacement of the malonate anion. Thus it has been used to introduce the ɑ-methylacetic acid unit at a remote position, asin the -alkylation of unsaturated ketones, in which the displaced malonate anion reacts with the initially-formed ɑ-bromo ketone. This process has been termed "transfer alkylation": J. Am. Chem. Soc., 94, 1790 (1972):
• Brominating agent, more reproducible than bromine, for ester enolates: Rec. Trav. Chim., 96, 72 (1977).