Substance
ID:73358
Names and Identifiers
IUPAC Traditional name
ofloxacin
IUPAC name
7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
Synonyms
OfloxacinDL-8280FlobacinHOE-280FloxinExocin
Registration numbers
CAS Number
Properties
Pharmacology Properties
Target
topoisomerase
Product Information
Salt Data
Free Base
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Infection
Biological Activity:
Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class. Ofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase and topoisomerase IV, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division. [1]
Biological Activity:
Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class. Ofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase and topoisomerase IV, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division. [1]
Molecular Spectra
No Data Available
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References
• http://www.rxlist.com/floxin-drug.htm