Substance
ID:73333
Names and Identifiers
Synonyms
mitrexSuminatImitrexImigranSumitrexSumatriptan succinate
IUPAC Traditional name
succinic acid; sumatriptan
IUPAC name
1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide; butanedioic acid
Registration numbers
CAS Number
Properties
Pharmacology Properties
Target
5-HT receptor
Product Information
Salt Data
Succinate
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Neurological Disease
Biological Activity:
Sumatriptan succinate(mitrex, Imigran) is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches. Sumatriptan is structurally similar to serotonin (5HT), and is a 5-HT (types 5-HT1D and 5-HT1B) agonist. The specific receptor subtypes it activates are present on the cranial arteries and veins. Acting as an agonist at these receptors, Sumatriptan reduces the vascular inflammation associated with migraine. [1]
Biological Activity:
Sumatriptan succinate(mitrex, Imigran) is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches. Sumatriptan is structurally similar to serotonin (5HT), and is a 5-HT (types 5-HT1D and 5-HT1B) agonist. The specific receptor subtypes it activates are present on the cranial arteries and veins. Acting as an agonist at these receptors, Sumatriptan reduces the vascular inflammation associated with migraine. [1]
Molecular Spectra
No Data Available
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References
• http://www.rxlist.com/imitrex-drug.htm