Substance
ID:73183
Names and Identifiers
Synonyms
DTICDacarbazineDtic-Dome
IUPAC name
5-[(1E)-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide
IUPAC Traditional name
dacarbazine
Registration numbers
CAS Number
Properties
Product Information
Salt Data
Free Base
Pharmacology Properties
Target
DNA/RNA synthesis
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: Cancer
Biological Activity:
Dacarbazine(DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various cancers, among them malignant melanoma, Hodgkin lymphoma, sarcoma, and islet cell carcinoma of the pancreas. [1]Dacarbazine belongs to the family of chemicals known as alkylating agents. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. [2]Dacarbazine is normally administered by injection (a shot) or intravenous infusion (IV) under the immediate supervision of a doctor or nurse. [1]
Biological Activity:
Dacarbazine(DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various cancers, among them malignant melanoma, Hodgkin lymphoma, sarcoma, and islet cell carcinoma of the pancreas. [1]Dacarbazine belongs to the family of chemicals known as alkylating agents. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. [2]Dacarbazine is normally administered by injection (a shot) or intravenous infusion (IV) under the immediate supervision of a doctor or nurse. [1]
Molecular Spectra
No Data Available
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References
• http://www.cancer.gov/drugdictionary/?CdrID=39768