Substance
ID:73156
Names and Identifiers
Synonyms
Emend)AprepitantMK-869L-754030
IUPAC Traditional name
@aprepitant
IUPAC name
3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
Registration numbers
CAS Number
Properties
Physical Property
Solubility
DMSO
Safety Information
Storage Condition
-20°C
Pharmacology Properties
Target
substance P
Product Information
Salt Data
Free Base
Molecule Details
Research Area: Neurological Disease
Biological Activity:
Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor. Aprepitant is used for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting.[1]References on Aprepitant (MK-0869)[1] http://en.wikipedia.org/wiki/Aprepitant, ,
Biological Activity:
Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor. Aprepitant is used for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting.[1]References on Aprepitant (MK-0869)[1] http://en.wikipedia.org/wiki/Aprepitant, ,
Molecular Spectra
No Data Available
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References
• http://www.search.com/reference/Aprepitant