Substance
ID:73135
Names and Identifiers
IUPAC name
dichloroplatinumdiamine
Synonyms
Cisplatin
IUPAC Traditional name
diamminedichloroplatinum
Registration numbers
CAS Number
Properties
Physical Property
Solubility
DMSO
Product Information
Salt Data
Free Base
Safety Information
Storage Condition
-20°C
Molecule Details
Research Area: cancer
Biological Activity:
Cisplatin is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, small cell lung cancer, ovarian cancer, lymphomas, and germ cell tumors. It was the first member of a class of anti-cancer drugs which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA which ultimately triggers apoptosis . [1]
Biological Activity:
Cisplatin is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, small cell lung cancer, ovarian cancer, lymphomas, and germ cell tumors. It was the first member of a class of anti-cancer drugs which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA which ultimately triggers apoptosis . [1]
Molecular Spectra
No Data Available
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References
• Rebillard A et al. Curr Med Chem. 2008;15(26):2656-63