Substance
ID:722197
Names and Identifiers
IUPAC name
2-(pyridin-2-yl)ethan-1-ol
IUPAC Traditional name
2-pyridineethanol
Synonyms
2-(2-Pyridyl)ethanol2-(2-Hydroxyethyl)pyridine2-Pyridineethanol2-(2-羟基乙基)吡啶
Registration numbers
EC Number
CAS Number
MDL Number
Beilstein Number
Properties
Product Information
Purity
99%
Safety Information
Storage Warning
Hygroscopic
GHS Hazard statements
H315-H319-H335-H227
TSCA Listed
是
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P210-P305+P351+P338-P302+P352-P321-P405-P501A
European Hazard Symbols
Irritant (Xi)Safety Statements
26-37
RTECS
UT2970450
Risk Statements
36/37/38
Physical Property
Flash Point
117°C(243°F)
Boiling Point
235-238°C
Refractive Index
1.5370
Melting Point
-8°C
Density
1.095
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Has also been used for carboxyl protection of amino acids. Pet esters are stable to both mildly acidic and basic conditions used to cleave such groups as Boc and Fmoc, and also to hydrogenolysis. Cleavage is by quaternization with methyl iodide in the presence of mild base: Tetrahedron Lett., 25, 3971 (1984); Angew. Chem. Int. Ed., 23, 716 (1984). See Appendix 6.
• Reagent for protection of the 5'-phosphate of nucleotides as 2-pyridylethyl (Pet) esters. The group can be introduced by DCC-coupling, is stable to mild base, but can be cleaved by methoxide in pyridine-methanol: Chem. Ber., 103, 1032 (1970).