Substance
ID:719819
Names and Identifiers
IUPAC Traditional name
acetonitrile
Synonyms
Methyl cyanideCyanomethaneAcetonitrile乙腈
IUPAC name
acetonitrile
Registration numbers
Beilstein Number
CAS Number
EC Number
MDL Number
Merck Index
Properties
Safety Information
European Hazard Symbols
Harmful (X)
Flammable (F)TSCA Listed
是
Packing Group
II
Risk Statements
11-20/21/22-36
Hazard Class
3
RTECS
AL7700000
Safety Statements
16-36/37
GHS Precautionary statements
P210-P241-P303+P361+P353-P305+P351+P338-P403+P235-P501A
UN Number
UN1648
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Flammable gases, category 1
Flammable aerosols, categories 1,2
Flammable liquids, categories 1,2,3
Self-reactive substances and mixtures, Types B,C,D,E,F
Pyrophoric liquids, category 1
Pyrophoric solids, category 1
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3
Organic peroxides, Types B,C,D,E,F
GHS Hazard statements
H225-H302-H312-H332-H319
Physical Property
Flash Point
5°C(41°F)
Boiling Point
80-82°C
Density
0.786
Melting Point
-48°C
Refractive Index
1.3440
Product Information
Purity
99%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• For use in the mild conversion of amides to nitriles, see Benzamide, A10501.
• Undergoes the Ritter reaction with alcohols or olefins in the presence of acid to give N-substituted acetamides. For benzylic alcohols, modified conditions employing boron trifluoride etherate give high yields: Synth. Commun., 24, 601 (1994). For an example, see 4-Methylbenzyl alcohol, A15315.
• Polar aprotic solvent for a wide variety of reactions, including nucleophilic substitutions, oxidations, reductions and organometallic reactions. Widely used with crown ethers for the generation of 'naked' anions from their salts; see, e.g. 18-Crown-6, A11249. Preferred solvent for RuO4 oxidations, due to its coordinating ability; see Ruthenium(III) chloride hydrate, 11043.