Substance
ID:719757
Names and Identifiers
IUPAC Traditional name
dimethylglycine
IUPAC name
2-(dimethylamino)acetic acid
Synonyms
N,N-DimethylglycineN,N-二甲基甘氨酸Dimethylaminoacetic acid
Properties
Safety Information
GHS Hazard statements
H302
GHS Precautionary statements
P264-P270-P301+P312-P330-P501A
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Storage Warning
Hygroscopic
TSCA Listed
是
RTECS
MB9865000
Product Information
Purity
98+%
Physical Property
Melting Point
179-183°C
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Additive which promotes the Heck coupling reaction of unactivated aryl chlorides with alkenes, catalyzed by Pd(II) in the presence of Tetraphenylphosphonium chloride, A10575: Angew. Chem. Int. Ed., 37, 481 (1998). The combination with Bis(benzonitrile)dichloropalladum constitutes a highly active phosphine-free catalyst system for Heck reactions of aryl bromides: Tetrahedron Lett., 39, 8449 (1998); see also: Tetrahedron Lett., 39, 8449 (1998). Promotes the copper(I)-catalyzed Ullmann-type coupling of aryl bromides and iodides with amines: Org. Lett., 5, 2453 (2003), and phenols: Org. Lett., 5, 3799 (2003), to give substituted anilines and diaryl ethers, respectively. Aryl iodides can also be coupled with aliphatic alcohols to give aryl alkyl ethers: Synlett, 243 (2007). In combinatiion with CuI, vinyl halides with phenols give aryl vinyl ethers: Synlett, 1767 (2005).