Substance

ID:719624

N,N'-Diisopropylcarbodiimide

Names and Identifiers
IUPAC name
(propan-2-yl)({[(propan-2-yl)imino]methylidene})amine
IUPAC Traditional name
diisopropylcarbodiimide
Synonyms
DICN,N'-DiisopropylcarbodiimideN,N'-二异丙基碳二酰亚胺
Registration numbers
CAS Number
Beilstein Number
EC Number
MDL Number
Properties
Physical Property
Flash Point
33°C(91°F)
Boiling Point
145-148°C
Density
0.810
Refractive Index
1.4330
Product Information
Purity
99%
Safety Information
Hazard Class
6.1
Storage Warning
Moisture Sensitive
GHS Hazard statements
H330-H315-H317-H335-H334-H318-H226
UN Number
UN2929
Safety Statements
4-9-20-23-26-28-36/37/39-45
GHS Pictograms
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS05
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
GHS06
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS02
Flammable gases, category 1
Flammable aerosols, categories 1,2
Flammable liquids, categories 1,2,3
Self-reactive substances and mixtures, Types B,C,D,E,F
Pyrophoric liquids, category 1
Pyrophoric solids, category 1
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3
Organic peroxides, Types B,C,D,E,F
European Hazard Symbols
Highly toxic Highly toxic (T+)
Packing Group
II
GHS Precautionary statements
P210-P303+P361+P353-P304+P340-P305+P351+P338-P320-P405-P501A
Risk Statements
10-26-37/38-41-42/43
RTECS
FF2175000
TSCA Listed
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Reagent for peptide coupling: J. Org. Chem., 44, 5000 (1979). Has the advantage over N,N'-Dicyclohexylcarbodiimide, A10973 in solid phase peptide syntheses that the urea by-product is more soluble in organic solvents and hence more readily separated from the polymer support. For peptide reagents, see Appendix 6.