Substance
ID:719416
Names and Identifiers
IUPAC Traditional name
2,2,6,6-tetramethylpiperidine
IUPAC name
2,2,6,6-tetramethylpiperidine
Synonyms
2,2,6,6-四甲基哌啶2,2,6,6-Tetramethylpiperidine
Registration numbers
CAS Number
EC Number
MDL Number
Beilstein Number
Properties
Product Information
Purity
98+%
Safety Information
Risk Statements
10-22-34
GHS Pictograms
Flammable gases, category 1
Flammable aerosols, categories 1,2
Flammable liquids, categories 1,2,3
Self-reactive substances and mixtures, Types B,C,D,E,F
Pyrophoric liquids, category 1
Pyrophoric solids, category 1
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3
Organic peroxides, Types B,C,D,E,F
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
European Hazard Symbols
Harmful (X)
Corrosive (C)RTECS
TN4220000
TSCA Listed
是
Packing Group
III
GHS Hazard statements
H314-H318-H226-H302
Safety Statements
26-36/37/39-45
Hazard Class
3
GHS Precautionary statements
P280-P305+P351+P338-P309-P310
UN Number
UN2733
Physical Property
Melting Point
-59°C
Density
0.832
Refractive Index
1.4440
Boiling Point
152-154°C
Flash Point
34°C(93°F)
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Lithiation gives a highly-hindered, non-nucleophilic strong base; see, e.g. Org. Synth. Coll., 6, 571 (1988);9, 426 (1998); Tetrahedron, 50, 3099 (1994). For use in selective isomerization of epoxides to aldehydes, see: J. Chem. Soc., Chem. Commun., 2103 (1994). For a study of the influence of TMEDA and related chelating ligands on the solution structure of the lithiated base, see: J. Org. Chem., 62, 5748 (1997). The Mg derivative, obtained by reaction with n-BuMgCl, is also an effective strong base which has been used in the regioselective ortho-metallation of pyridine carbamates and carboxamides: J. Org. Chem., 60,8414 (1995).