Substance
ID:718040
Names and Identifiers
IUPAC name
2-bromo-5-nitrothiophene
IUPAC Traditional name
2-bromo-5-nitrothiophene
Synonyms
2-Bromo-5-nitrothiophene2-溴-5-硝基噻吩
Registration numbers
MDL Number
CAS Number
EC Number
Beilstein Number
Properties
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Safety Statements
26-37
TSCA Listed
否
GHS Hazard statements
H315-H319-H335
European Hazard Symbols
Irritant (Xi)Risk Statements
36/37/38
GHS Precautionary statements
P261-P305+P351+P338-P302+P352-P321-P405-P501A
Physical Property
Boiling Point
235-237°C
Melting Point
42-46°C
Product Information
Purity
97%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Undergoes vicarious nucleophilic substitution of hydrogen at the 4-position; e.g., with chloromethyl phenyl sulfone and base, 2-bromo-5-nitro-4-(phenylsulfonylmethyl)thiophene is formed in 92% yield: Tetrahedron, 51, 8339 (1995). For an analogous example and reaction scheme, see 2-Nitrothiophene, A17464.
• For a review of vicarious nucleophilic substitution in heterocyclic compounds, see: Synthesis, 103 (1991).