Substance
ID:717609
Names and Identifiers
IUPAC name
propane-1,3-dithiol
IUPAC Traditional name
1,3-propanedithiol
Synonyms
1,3-Propanedithiol1,3-丙二硫醇Trimethylene mercaptan
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
Merck Index
Properties
Safety Information
European Hazard Symbols
Irritant (Xi)UN Number
UN3334
GHS Hazard statements
H315-H319-H335-H227
Risk Statements
36/37/38
TSCA Listed
是
RTECS
TZ2585500
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P210-P305+P351+P338-P302+P352-P321-P405-P501A
Safety Statements
23-26-37-60
Hazard Class
9
Physical Property
Boiling Point
168-170°C
Refractive Index
1.5400
Melting Point
-79°C
Solubility
Slightly soluble in water. Miscible with alcohol, ether, chloroform, ether
Density
1.077
Flash Point
63°C(145°F)
Product Information
Purity
97%
Molecule Details
No Data Available
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Molecular Spectra
No Data Available
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References
• Precursor of cyclic dithioacetal (1,3-dithiane) derivatives of carbonyl compounds. The protection step is catalyzed by Lewis acids, e.g. BF3 etherate: Tetrahedron Lett., 871 (1971), TiCl4: Tetrahedron Lett., 24, 1289 (1983), Aluminum trifluoromethanesulfonate, B20785, or Indium(III) trifluoromethanesulfonate, 40131. Diothioacetalization can be accomplished under neutral, solvent-free conditions using Lithium trifluoromethanesulfonate, 39322, as catalyst: Tetrahedron Lett., 40, 4055 (1999). For the preparation of monocyclic dithioacetals of ?-diketones at low temperature in the presence of BF3 etherate, see: Tetrahedron, 44, 2283 (1988).
• For deprotection methods and uses of 1,3-dithianes as acyl anion equivalents, see: 1,3-Dithiane, A10505.
• Alternatively, 1,3-dithianes can be prepared by alkylation with reactive gem-dihalides under phase-transfer conditions: Liebigs Ann. Chem., 1589 (1982).